Senior Clinical Research Associate (Argentina)
Remote, Argentina
We're expanding our capabilities across Latin America, and we're hiring a Senior Clinical Research Associate to support critical studies across Argentina!
As a Senior CRA you'll posses a wide-ranging and broad experience handling our most complex and advanced assignments.
Responsibilities will be dependent upon the type and timing of the program to which the Senior CRA is assigned and will, at a minimum, include start-up and study implementation activities, on-site monitoring of clinical research studies as well as on-going site management.
Incumbents are expected to be able to manage appropriately sized or complex clinical trials, and support Clinical Trial Managers and/or Project Managers with trials as required.
An increased focus on training and mentoring junior staff members may be expected.
Responsibilities:
Independently oversees all aspects of study site management to ensure patient safety is protected, quality of data generated by managed sites resulting in consistently low query levels and in acceptable Quality Assurance reports
Provides guidance at the site and project level towards audit readiness standards and supports preparation for audit and required follow-up actions
Establishes, updates, tracks and maintains study specific trial management tools/systems, and status reports
Manages site start up procedures including the feasibility and recruitment of potential investigators, preparation of EC/IRB submissions, collection and review of regulatory documents, review and adaptation in Patient Informed Consents, notifications to IRB, EC and regulatory authorities, as appropriate, translation of study related documentation, organization of meetings and other tasks as instructed by the Clinical Trial Manager/Project Manager
If required, assists the negotiation of study budgets and the execution of investigator contracts under directions of Site Contract Management department/designee
Verifies the process of obtaining informed consent has been adequately performed and documented for each subject/patient, as required/appropriate.
Assesses factors that might affect subject/patient's safety and clinical data integrity at an investigator/physician site such as protocol deviation/violations and pharmacovigilance issues
Independently conducts all forms of site visits, including pre-study/qualification, initiation, routine monitoring, and close-out visits, in accordance with the protocol, local laws, ICH-GCP and Precision SOPs.
Performs Monitoring Oversight Visits to assess other CRA team members.
Prepares and submits for review, accurate and timely monitoring reports from all site visits (on-site and remote)
Documents activities via confirmation letters, follow-up letters, trip reports, communication logs, and other required project documents as per SOPs, Clinical Monitoring Plan/Site Management Plan and client requirements.
Supports subject/patient recruitment, retention and awareness strategies.




Enters data into tracking systems as required to track all observations, ongoing status and assigned action items to resolution
Routinely reviews the Investigator Site File (ISF) for accuracy, timeliness and completeness.
Reconciles contents of the ISF with the Trial Master File (TMF).
Ensures the investigator/physician site i data and protect people.
At Proofpoint you'll be part of a global team that breaks barriers to redefine cybersecurity guided by our BRAVE core values:
Bold in how we dream and innovate Responsive to feedback, challenges and opportunities Accountable for results and best in class outcomes Visionary in future focused problem-solving Exceptional in execution and impact
Proofpoint is looking for a Staff Data Engineer to join our growing Data Platform team.
In this senior individual‐contributor role you will design, build, and operate the large‐scale data infrastructure that underpins Proofpoint's cybersecurity products and analytics.
You will work across the full data lifecycle—ingestion, transformation, orchestration, and delivery—using modern cloud‐native tooling on AWS.
You'll partner with data scientists, product engineers, and business stakeholders to turn raw data into reliable, governed, and performing data assets that drive product decisions and customer value.
What You'll Do
Design and implement scalable, reliable data pipelines using AWS Glue (PySpark and Glue Studio) to ingest and transform petabyte‐scale datasets stored in Amazon S3.
Build and maintain our cloud data lake architecture on S3—defining partition strategies, file formats (Parquet, ORC, Delta), and data‐catalog schemas in AWS Glue Data Catalog.
Establish and enforce data quality standards—implement validation frameworks, anomaly detection, and SLA‐driven alerting to ensure data reliability.
Define and drive engineering best practices: code reviews, CI/CD for data pipelines, Infrastructure‐as‐Code (Terraform/CDK), and DataOps principles.
Serve as a technical leader and mentor—conduct design reviews, guide junior engineers, and influence the team's technical roadmap.
Collaborate closely with data scientists, ML engineers, and product managers to translate business requirements into robust data models and pipeline specifications.
Champion data governance, lineage tracking, and privacy‐by‐design principles across all data assets.
Troubleshoot and resolve production incidents, perform root‐cause analysis, and drive preventive improvements.
Contribute to architecture decision records (ADRs) and technical documentation.
What You Bring to the Team
Required
8+ years of professional software or data engineering experience,



with at least 4 years focused on cloud data platforms.
Deep expertise with AWS data services: S3 (lifecycle policies, event notifications, encryption), AWS Glue (ETL jobs, Crawlers, Data Catalog, Glue Studio), and Amazon Athena (query optimization, workgroups, federated queries).
Strong Python programming skills; proficiency writing production‐grade PySpark or Spark (Scala) for large‐scale data transformation.
Solid SQL fundamentals—ability to write and tune complex analytical queries.
Excellent communication skills—able to present technical trade‐offs clearly to both engineering and non‐engineering stakeholders.
Proven experience mentoring engineers and leading technical design discussions.
Bachelor's degree in Computer Science, Engineering, or a related technical field (or equivalent practical experience).
Nice to Have
Experience with real‐time / streaming data processing using Apache Kafka, Amazon Kinesis, or AWS Glue Streaming ETL.
Familiarity with AWS Lake Formation for fine‐grained access control and data governance.
Knowledge of Amazon Redshift or other cloud data warehouses.
Experience with data quality frameworks (Great Expectations, Deequ, or similar).
Background in cybersecurity, threat intelligence, or security analytics data.
AWS Certified Data Engineer - Associate or AWS Certified Solutions Architect certification.
Contributions to open‐source data engineering projects or publications.
Why Proofpoint?
Competitive compensation
Comprehensive benefits
Career success on your terms
Flexible work environment
Annual wellness and community outreach days
Always on recognition for your contributions
Integral collaboration and networking opportunities
Our Culture
Our cultvestigative staff, and clients with a high level of proficiency.
Demonstrated focus on continuous improvement, including the ability to make proactive assessments on how to make processes more efficient and people more effective.
#LI-AG2 #LI-REMOTE
Any data provided as a part of this application will be stored in accordance with our Privacy Policy.
For CA applicants, please also refer to our CA Privacy Notice .
Precision Medicine Group is an Equal Opportunity Employer.
Employment decisions are made without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status or other characteristics protected by law.
If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process or are limited in the ability or unable to access or use this online application process and need an alternative method for applying, you may contact Precision Medicine Group at ****** .
We use Artificial Intelligence (AI) to generate insights during the end to end application journey, including resume review and interviews .
Please review our Privacy Policy - Precision Medicine Group for more information.
#J-*****-Ljbffr

📌 Senior Clinical Research Associate (Argentina) Remote, Argentina (Santa Fe)
🏢 Precision Medicine Group
📍 Santa Fe